Clinical Osteoporosis Support™ is a dietary supplement to
support bone structure and function. This dietary supplement
is focused on comprehensive nutritional support, using principles
of protomorphogenesis plus bone-boosting agents; and
it is one component of a holistic plan to provide nutritional
support for the structure and functions of bones. Combat
against osteoporosis is part of “the Antiporosis Plan”. This plan
consists of: Public education, Positive lifestyle change, Physical
Activity, Bone Density Screening, Bone Boosting Diet, Injury
Prevention, Risk Factor Assessment, and dietary supplements
e.g. Clinical Osteoporosis Support™. Drugs for osteoporosis
treatment should be applied where indicated.
DIETARY SUPPLEMENTS FOR BONE HEALTH
Many dietary supplements for bone building have focused
on one or two known, bone-building, natural substances and
are incomplete in their formulation. Some use calcium alone,
some use ipriflavone alone and some use general mineral
formulae. These approaches have been superseded in modern
nutraceutical technology by the use of synergy (additive effects
of combined nutrients, botanicals or herbs).
The advanced, synergistic formulation of Clinical
Osteoporosis Support™ contains 1500mg of specially
prepared, eggshell calcium (Nature’s Calcium™). This form of
calcium contains at least 18 desirable trace elements in addition
to calcium, including Mg, S, Si and Boron. Controlled trials
of eggshell calcium show measurable increases in bone density
in post-menopausal females over a period of one year, with
superior effects over placebo or calcium carbonate (Schaafsma
et al, British Journal of Nutrition, 87, 3, 267-275, 2002).
Calcium is most effective when combined with Vitamin
D3. Magnesium is mandatory for bone building and magnesium
deficiency is associated with tissue resistance to the
actions of Vitamin D3 and parathyroid hormone. Clinical
Osteoporosis Support™ delivers calcium and magnesium in
a 2:1 ratio. Several trace elements are important in bone structure
and formation of calcium matrices, including: silicon,
boron, manganese, copper, zinc and strontium. The importance
of strontium in bone building has been highlighted in
recent research. These trace elements are variable components
of Clinical Osteoporosis Support™.
Research has shown a definite link between elevated levels
of blood homocysteine and osteoporosis. Vitamins B6, B12
and folic acid are part of Clinical Osteoporosis Support™,
in order to help promote a healthy blood homocysteine level.
Antioxidant actions are important in bone structure and
mineralization e.g. vitamin C, curcuminoids and isoflavones.
While a wide range of minerals and vitamins are necessary
in an optimal bone-supporting supplement, bone-boosting
botanical extracts or derivatives have an evidence-base for use in
supporting bone structure and function. Diets supplemented
with soy protein containing isoflavones are a variably effective
way of preventing post-menopausal bone loss, by inhibition
of osteoclastic activity and other mechanisms. Bone density
measurements in prospective clinical studies show an ability
of soy isoflavones and ipriflavone (a flavonoid) to help
improve bone density. There are several human clinical trials
showing favorable effects of ipriflavone as a safe, bone builder
and ipriflavone has prescription status for use as a drug in
several countries. In the U.S., ipriflavone is available as a
dietary supplement and it is used in Clinical Osteoporosis
Support™. This description does not imply treatment claims.
CLINICAL OSTEOPOROSIS SUPPORT™
Many drugs that are used in the treatments of established
osteoporosis have onerous side effects (e.g. bisphosphonates,
NSAID etc.). It is never too early or too late to consider a
combat against osteoporosis, but prevention is the key initiative.
While osteoporosis is more frequent in women than men,
the clinical outcome of thin bones is more devastating in men
than women. Peak bone mass occurs in females around the
age of 34 years and from this point onwards, bone density is
“often downhill”. Nutrient deficiency in children contributes
to osteoporosis in adults, especially lifelong calcium deficiency.
Clinical Osteoporosis Support ™ is for use in mature adults.
Bone care and the prevention of osteoporosis involve holistic